Pulmonary hypertension is a complex disease that causes significant morbidity and mortality and is clinically characterised by an increase in pulmonary vascular resistance. The histopathology is marked by vascular proliferation/fibrosis, remodelling, and vessel obstruction. In this book, the authors present current research in the study of the pathogenesis, diagnosis and treatment of pulmonary hypertension. Topics discussed include the pathophysiology of Eisenmenger Syndrome (ES) and an evaluation of differences between ES and pulmonary arterial hypertension; pulmonary endarterectomy as an effective treatment for chronic thromboembolic pulmonary hypertension; liver transplantation and pulmonary hypertension and the possible aetiologies of pulmonary hypertension in Down Syndrome children.

Percutaneous coronary intervention (PCI) has entered its third decade, as it had gone through a PTCA era, BMS era, and entered into the DES era. This book summarises information gathered from recent literature in the field of PCI, focusing on PCI procedures, adjunctive pharmacotherapy and adverse effects. The editor has put together a comprehensive, in-depth guide to PCI, which has seen great advances in the understanding and management of coronary artery disease in recent years. The book examines all aspects of PCI in detail, in isolation and in combination with procedures, or medical uses and its adverse effects, to fulfil the aim of helping healthcare professionals and medical students to better understand and manage PCI problems in the DES era.

Pulmonary embolism and chronic thromboembolic pulmonary hypertension are health devastating diseases with considerable morbidity and mortality. Pulmonary thrombectomy and pulmonary thromboendarterectomy are the procedures designed to treat pulmonary embolism and chronic thromboembolic pulmonary hypertension with very good early and long term effects. This book presents the latest research in this growing field. As a subsidiary and supporting knowledge to the pulmonary thromboendarterectomy, this book also provides knowledge relevant to the anatomy and physiology of respiratory system; pulmonary circulation and bronchial circulation; the physiology and pathophysiology of coagulation and fibrinolysis; the recent progress in thrombosis, anticoagulant and thrombolysis, deep vein thrombosis, acute pulmonary embolism and chronic thromboembolic pulmonary hypertension.